FAQ: Xdemvy in Seattle, WA

XDEMVY is a prescription eye drop containing lotilaner 0.25% that is FDA-approved to treat Demodex blepharitis. It provides a targeted treatment for the Demodex mites responsible for this eyelid condition rather than simply addressing surface symptoms.

Demodex blepharitis is inflammation of the eyelids associated with an overpopulation of microscopic Demodex mites around the eyelashes. Our eye doctors in Seattle can evaluate persistent eyelid irritation and determine whether Demodex is contributing to the problem and whether XDEMVY is appropriate.

Patients may notice eyelid redness, irritation, itching, burning, crusting around the eyelashes, or a gritty sensation. One particularly important sign is the presence of collarettes, which are cylindrical deposits that collect around the base of the eyelashes and are strongly associated with Demodex blepharitis.

At Roosevelt Vision in Seattle, WA, we examine the eyelids, eyelashes, and ocular surface closely for characteristic signs of Demodex blepharitis, especially collarettes at the lash line. An accurate diagnosis matters because other conditions, including dry eye, allergies, and other forms of blepharitis, can cause similar symptoms.

Adults with confirmed Demodex blepharitis may be candidates for XDEMVY. We first evaluate the eyelids and overall eye health so we can distinguish Demodex-related inflammation from other causes and recommend treatment based on the findings.

XDEMVY contains lotilaner, which acts directly on Demodex mites by disrupting specific chloride channels in the mites, resulting in paralysis and death. For patients with Demodex blepharitis, this allows treatment to target the underlying mite infestation rather than focusing only on eyelid debris or irritation.

The FDA-approved dosing schedule for XDEMVY is one drop in each eye twice daily, approximately 12 hours apart, for six weeks. We advise our patients to follow the prescribed schedule consistently and complete the treatment course as directed.

The standard XDEMVY treatment course is six weeks. Patients may experience changes at different points during treatment, so we recommend using the medication for the full prescribed course rather than stopping simply because the eyelids begin to feel or look better.

The most common side effect reported with XDEMVY is temporary stinging or burning when the drops are applied, which occurred in 10% of patients in clinical trials. Less common ocular reactions included chalazion or hordeolum and punctate keratitis. Patients should contact us if they develop concerning or persistent eye or eyelid reactions.

Yes, but patients should remove their contact lenses before applying XDEMVY. The lenses may be reinserted 15 minutes after the medication is administered. Following these instructions is important because an ingredient in XDEMVY may discolor soft contact lenses.

Patients who use more than one topical eye medication should separate XDEMVY from other ophthalmic drops by at least five minutes. We also recommend telling us about all prescription drops, over-the-counter products, and eyelid treatments you currently use so we can provide clear instructions.

If you miss an XDEMVY dose, continue with your next regularly scheduled dose. Patients should not change the prescribed schedule on their own to compensate for a missed application.

XDEMVY is specifically approved for Demodex blepharitis, not dry eye disease. However, Demodex-related eyelid inflammation can occur alongside ocular surface irritation and dry eye symptoms. At Roosevelt Vision in Seattle, WA, we evaluate the complete picture so we can address Demodex blepharitis as well as any separate dry eye concerns.

The safety and effectiveness of XDEMVY have not been established for patients younger than 18. For children or teenagers with eyelid redness, crusting, itching, or other symptoms, we recommend an eye examination so we can identify the cause and select age-appropriate care.

At Roosevelt Vision in Seattle, WA, we take a thorough approach to diagnosing and treating Demodex blepharitis. We carefully evaluate your eyelids, eyelashes, and ocular surface to confirm the cause of your symptoms before recommending treatment. If XDEMVY is appropriate, we provide clear guidance on how to use it correctly and monitor your response so your care is tailored to your eye health and needs.